Science and Technology 科学技術 Vol.23 / #Coronavirus #コロナウイルス Vol.25

All the below links and tweets are in English.

取り急ぎ以下(内容事項一部抜粋ご参考まで)貼っておきます。

Science and Technology Vol.59 (physics, chemistry, etc.)
debris ball,gravity water RenewableEnergy
Science and Technology Vol.58 (Hydrogen, Artificial Intelligence, Coronavirus, etc.)
Hydrogen-FuelCell,Electric-Car agriculture-robotics-drones Earth,Mars 8086-processor
Science and Technology Vol.57 (Artificial Intelligence, Coronavirus, etc.)
RheumatoidArthritis,baricitinib,AI COLCORONA,Colchicine architecture
Science and Technology Vol.56 (Artificial Intelligence, Hydrogen, etc.)
AI,DrugDevelopment DataScience,MachineLearning composite-polymer CleanEnergy battery car AtmosphericChemistry ammonia

内容例(各回ツイートもご覧ください)
以下、順に、
59:@compoundchem、@FCHEA_News、@thecrimson、@ScienceAlert,@ConversationUK
58:@FutureOfAg,@AlxMcFarland,@UniteAi、@plish,@ucrholly,UCRiverside,@TechXplore_com、@energynetworks、@TheICCT,@EUEnergyNews
57:@newyorker,@AIApgh、@entrepreneur,@sales_lms
56:@VentureBeat、@BD_Chamber,@BBCNews、@HydrogenCouncil,@h2_view、@LifeboatHQ,@Inceptive_Mind
SciTech59 water-treatment @compoundchem
SciTech59 electrolyzer-2018 @FCHEA_News
SciTech59 cheaper-renewable-storage @thecrimson
SciTech59 split-water-space @ScienceAlert,@ConversationEDU
SciTech58 AmphiSTAR @FutureOfAg,@AlxMcFarland,@UniteAi
SciTech58 robot-water-crops @plish,@ucrholly,UCRiverside@TechXplore_com
SciTech58 GasGoesGreen @energynetworks
SciTech58 heat-pumps @TheICCT,@EUEnergyNews
Coronavirus-reshape-architecture @newyorker @AIApgh
AI-change-work @entrepreneur,@sales_lms
use-less-data @VentureBeat
AI-created-medicine @BD_Chamber,@BBCNews
@HydrogenCouncil,@h2_view
POWERPASTE @LifeboatHQ,@Inceptive_Mind

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

上記事項の日本関連


https://twitter.com/MargaretSiegien/status/1327885901750542336

World 世界情勢等 Vol.12 / U.S.A. アメリカ Vol.164

All the below links are in English.

取り急ぎ以下(内容事項一部抜粋ご参考まで)貼っておきます。

World Vol.101 (U.S., etc.)
Europe Russia Arctic Nagorny-Karabakh Houthis CentralAsia Iran NuclearBrinkmanship Syria Myanmar dinosaur Colombia IlliberalDemocratic Duterte FL
World Vol.100 (U.S., etc.)
Europe Iran,Iraq Myanmar Arctic India NorthAfrica ParisClimateAgreement cows GlobalSupplyChains 5G immigration TreeCoverLoss SputnikV Sinopharm Facebook BanGoodsFromXinjiang UFOs CO
World Vol.98 (U.S., etc.)
TracerApp BeachEnergy-surrender hydroxychloroquine PolarizationDynamic NASA-Mars Czech Ecuador LatAm NZ,AU KY
World Vol.97 (U.S., finance, etc.)
CentralBanks MonetaryPolicy TravelRelatedServices-ServicesInflation BodPurchases mortgages CurrentPopulationsSurvey broadband ManuSurvey NewSTART Friedman Alaska OysterShells SuperBowl JeffBezos-StepDown wheat SC,LA
World Vol.96 (U.S.)
Walmart sharks-rays FEMA-VaccinationCosts UNA-MamavaLactationPod CDC-FederalMaskMandate PERSI gym AL,ID
World Vol.93 (The Wall Street Journal, AFP, Reuters, TIME, The Economist, The Washington Post)
GameStop DoomsdayClock
World Vol.90 (incl The New York Times, Bloomberg Politics)
vaccines Poland CountyLevel-RiskAssessments SpicyChickenMcNuggets NV
World Vol.89 (U.S. Congress, insurance, NZ)
StateFarm Progressive LibertyMutual Allstate Travelers Chubb Farmers AIG TheHartford amfam CNA Assurant AXA Allianz AmyConeyBarrett

内容例(各回ツイートもご覧ください) 
順に、
100:@calebwatney,@ppi、@TaraStraw,@CenterOnBudget,@Marketplace、@BrookingsFP,@thomaswright08
97:@RichmondFed、@centralbank_ie
89:@Zurich
BidenAdministration entrepreneur pp13-16 @calebwatney,@ppi
BidenAdministration HealthInsurance @TaraStraw,@CenterOnBudget,@Marketplace
multilateralism1 pp5-8 @BrookingsFP,@thomaswright08
BidenAdministration entrepreneur pp13-16 @calebwatney,@ppi
RichmondFed broadband
CentralBankOfIreland ReallyRich
@Zurich Insurance robot

Recent articles about Japan 日本関連英文記事 Vol.13(U.S. and Northeast Asia, earthquakes, etc.)


https://www.youtube.com/watch?v=ESg2WXbWLXg


https://twitter.com/themainichi/status/1373212972357713922


https://twitter.com/TheInsiderPaper/status/1373238142241710080


https://twitter.com/ethanb822/status/1373218196031823877

Science and Technology 科学技術 Vol.22 / #Coronavirus #コロナウイルス Vol.24

All the below links are in English.

取り急ぎ以下(黒字部分は内容事項一部抜粋ご参考まで)貼っておきます。

Science and Technology Vol.55 (Artificial Intelligence, Coronavirus, etc.)
knits bioenergy manufacturing industry40 DENSO SelfOptimizingPlant 5G Swapp SmartCities MilkRobot StarshipRobots AutonomousTractors
Science and Technology Vol.54 (Artificial Intelligence, Coronavirus, etc.)
IoT FacialRecognition MedicalImaging Automation,3Dprinters DataScience MonoclonalAntibodies ML SatelliteImages Google,Fitbit JohnVonNeumann ReceptorBindingDomain,RBD
Science and Technology Vol.53 (Coronavirus, Artificial Intelligence, etc.)
RoboticSurgery surveillance SmartCity AI,MachineLearning,VaccineManufacturing 5G,6G,IoT,BigData flu
Science and Technology Vol.52 (incl Coronavirus, Jupiter & Saturn)
mutated,mutate,mutations,mutants,variants,transmissable immunocompromised SickleCell,CRISPR PPE RampantMisinformation bacteria,PollutionMonitoring ImmuneHealth DeepSleep,WasteProducts microbiome digestion minerals,selenium ivermectin humidifier AnGes
Science and Technology Vol.51 (coronavirus vaccine, artificial intelligence, space, etc.)
Moderna Pfizer PolyethyleneGlycol,PEG anaphylaxis,allergy AI Hayabusa astronomy Shionogi

代表例(各回ツイートもご覧ください。)
以下順に、54. @geekwire,@allen_ai,@etzioni,@uwcse、53. @CDCgov、52. @BBCNews、51. @epfl_en,@HofSwitzerland。
@geekwire,@allen_ai,@etzioni,@uwcse
02212021 masks @CDCgov
UK PPE-recycle @BBCNews
CHUV_HUG @epfl_en @HofSwitzerland

Science and Technology 科学技術 Vol.21 / U.S.A. アメリカ Vol.133(Personal Protective Equipment #PPE, etc. 個人防護具等)

All the below links are in English.

取り急ぎ以下貼っておきます。

Science and Technology Vol.46 (personal protective equipment (PPE) suppliers/manufacturers)

New York Vol.38 (corporations: Henry Schein)

New York Vol.39 (corporations: Protective Industrial Products)

Pennsylvania Vol.15 (corporations: MSA Safety Incorporated)

North Carolina Vol.15 (corporations: Honeywell)

Ohio Vol.7 (corporations: Cardinal Health)

Ohio Vol.8 (corporations: Cintas Corporation)

Michigan Vol.12 (corporations: Gentex Corporation)

Michigan Vol.13 (corporations: Avon Protection)

Michigan Vol.14 (corporations: Carhartt)

Illinois Vol.15 (corporations: Grainger)

Illinois Vol.16 (corporations: Medline Industries)

Illinois Vol.17 (corporations: Klein Tools)

Wisconsin Vol.12 (corporations: Bradley Corporation)

Wisconsin Vol.13 (corporations: Conney Safety)

Minnesota Vol.10 (corporations: Ergodyne)

Minnesota Vol.11 (corporations: Fastenal Company)

Tennessee Vol.8 (corporations: MCR Safety)

Alabama Vol.8 (corporations: Motion Industries)

Florida Vol.12 (corporations: Accuform Signs)

Texas Vol.17 (corporations: Kimberly-Clark)

California Vol.31 (corporations: Moldex)

Science and Technology 科学技術 Vol.20 / U.S.A. アメリカ Vol.132 (pharmaceutical companies, etc. 製薬会社等)

All the below links are in English.

取り急ぎ以下貼っておきます。

Massachusetts Vol.27 (corporations: ImmunoGen)

Massachusetts Vol.26 (corporations: Ironwood Pharmaceuticals)

Massachusetts Vol.25 (corporations: Sarepta Therapeutics)

Massachusetts Vol.24 (corporations: Alexion Pharmaceuticals)

Massachusetts Vol.23 (corporations: Vertex Pharmaceuticals) / Switzerland Vol.8 (pharmaceutical corporations: CRISPR Therapeutics)

Massachusetts Vol.22 (corporations: Boston Scientific)

Massachusetts Vol.21 (corporations: Thermo Fisher Scientific)

New Jersey Vol.12 (corporations: Amicus Therapeutics)

New Jersey Vol.11 (corporations: PTC Therapeutics)

Pennsylvania Vol.13 (corporations: Inovio Pharmaceuticals)

Pennsylvania Vol.12 (corporations: Mylan)

Delaware Vol.8 (corporations: Incyte)

North Carolina Vol.13 (corporations: LabCorp)

Michigan Vol.11 (corporations: Stryker)

Illinois Vol.13 (corporations: GE Healthcare)

Illinois Vol.12 (corporations: Abbott Laboratories)

California Vol.30 (corporations: Intuitive Surgical)

California Vol.29 (corporations: Nektar Therapeutics)

California Vol.28 (corporations: Halozyme Therapeutics)

California Vol.27 (corporations: Illumina)

Texas Vol.16 (corporations: McKesson Corporation)

アメリカ最大手等10社強については当日本語サイトにおいても既に投稿済ですので、州ごとに適宜お探しください。
cf.
Massachusetts Vol.20 (corporations: Biogen)
Massachusetts Vol.19 (corporations: Moderna)
New York Vol.37 (corporations: Regeneron)
New York Vol.36 (corporations: Bristol Myers Squibb)
New York Vol.35 (corporations: Pfizer)
New Jersey Vol.10 (corporations: Merck (Merck Sharp & Dohme (MSD) outside the U.S. & Canada))
New Jersey Vol.9 (corporations: Johnson & Johnson)
Pennsylvania Vol.11 (corporations: CSL Behring) / Australia Vol.29
Maryland Vol.9 (corporations: Novavax)
Indiana Vol.8 (corporations: Eli Lilly)
Illinois Vol.14 (corporations: Baxter International)
Illinois Vol.11 (corporations: AbbVie)
California Vol.26 (corporations: Gilead Sciences)
California Vol.25 (corporations: Amgen)

#Coronavirus #コロナウイルス Vol.23(vaccines, etc. ワクチン等)

All the below link/tweets are in English.

取り急ぎ以下貼っておきます。

Science and Technology Vol.50 (coronavirus vaccine)  Vaccination SideEffects,AdverseReactions,AllergicReaction,AnaphylaxisReaction,PotentialTriggers,AllergyConcerns …

関連する最近のツイート


https://twitter.com/Daily_Express/status/1352246043845517315


https://twitter.com/wiltscouncil/status/1350844347793747968


https://twitter.com/POLITICOEurope/status/1351213890621886468


https://twitter.com/tamer_hadi/status/1352682427836207104


https://twitter.com/timesofindia/status/1351155661078474756

なお、リンク、ツイート及び記事を当サイトに貼る目的は、当サイトを訪れた方々が色んな情報に触れ満足されることです。弊社としては、煽る等の目的はもちろん常々ありませんし、現実にツイッター上に流れているものをなるべく予断や偏り無く時間の許す限りで一応貼っています。
Please note: the purpose we paste tweets on this website is that the visitors to this site will be satisfied with the visits because they can see various information here. Of course, we always have no intention of agitation, etc. We just paste tweets, which are actually on Twitter, with as little prejudication and bias as possible, as time permits.

Science and Technology 科学技術 Vol.19 / #Coronavirus #コロナウイルス Vol.22(pharmaceutical products 医薬品 Vol.8:drugs 治療薬)

All the below links and excerpts are in English.

Sarilumab (Kevzara®) に係るリンクと当方作成の抜粋を取り急ぎ以下のとおり貼っておきます。
cf.
Science and Technology 科学技術 Vol.14 / #Coronavirus #コロナウイルス Vol.15(pharmaceutical products 医薬品 Vol.6:drugs 治療薬) Tocilizumab
Science and Technology 科学技術 Vol.15 / #Coronavirus #コロナウイルス Vol.16(pharmaceutical products 医薬品 Vol.7:drugs 治療薬)

Clinicians encouraged to consider tocilizumab or sarilumab in treatment of hospitalised COVID-19 patients (07/01/2021) | @PJOnline_News,@robinson_julia
… The new advice, which is due to be published on 8 January 2020, follows results released from the Randomised, Embedded, Multi-factorial, Adaptive Platform Trial for Community-Acquired pneumonia (REMAP-CAP), which suggested that tocilizumab and sarilumab, which are both IL-6 receptor antagonists, led to a 24% reduced risk of mortality, when administered to patients within 24 hours of entering intensive care. …
At the time of full analysis, 353 patients had been assigned to tocilizumab, 48 to sarilumab and 402 to standard care. The majority of patients were also treated with corticosteroids, such as dexamethasone, and were receiving respiratory support.
The trial data yielded an odds ratio of 1.64 for a better outcome with tocilizumab, and 1.76 for sarilumab, compared to no immune modulation, with a high degree of statistical certainty.
…Anthony Gordon…
Gino Martini, chief scientist at the Royal Pharmaceutical Society…
Tocilizumab and sarilumab have already been added to the government’s export restriction list, which bans companies from buying medicines meant for UK patients and selling them on for a higher price in another country. This will protect supply for UK patients by enforcing regulatory action on those who flout the restrictions.

Roche’s Actemra, Regeneron’s Kevzara win U.K.’s favor in COVID-19 after study shows 24% drop in death risk (01/08/2021) | @FiercePharma,@arleneweintraub
The question of whether seriously ill COVID-19 patients can benefit from anti-inflammatories like Roche’s Actemra and Sanofi and Regeneron’s Kevzara has dogged practitioners in the United States thanks to conflicting clinical trial results.
The United Kingdom, on the other hand, has reached a definitive answer on the two drugs, both of which are IL-6 inhibitors: They significantly reduce the risk of death in COVID-19 patients needing intensive care, and they should be used to ease the pressure hospitals are now facing as the coronavirus pandemic continues to intensify, the country’s National Institute for Health Research (NIHR) said Thursday.
The recommendation came after data from an NIHR-sponsored study showed that Actemra and Kevzara can cut hospital stays for COVID-19 patients admitted to intensive care by 10 days and can lower the risk of death by 24% in patients who receive either drug within a day of admission. That finding prompted the U.K. government to recommend to the National Health Service (NHS) that IL-6 inhibitors be rolled out for the treatment of COVID-19. …

UK Covid patients to receive new drugs tocilizumab and sarilumab that reduce death risk by 24% (w Video; 01/08/2021) | @EveningStandard,@HattieBrewis
… NHS patients admitted to the country’s intensive care units will be able to receive tocilizumab and sarilumab, which have also been found to reduce the time coronavirus sufferers need to spend in hospital by up to 10 days. …
It comes after results from the Government-funded REMAP-CAP clinical trial showed that both drugs reduced the risk of mortality by 8.5 per cent when administered to patients within a day of entering intensive care alongside a corticosteroid, such as dexamethasone.
Professor Anthony Gordon, chair in anaesthesia and critical care at Imperial College London and a consultant in intensive care medicine at Imperial College Healthcare NHS Trust…
Hospital mortality was 27.3 per cent among patients receiving tocilizumab or sarilumab, compared with 35.8 per cent of patients in the control group who did not receive the drugs, the researchers said.
Treatment with tocilizumab or sarilumab is thought to cost somewhere between £750 and £1,000 and is administered intravenously either as a one or two dose regime.
Professor Gordon added: “For every 12 patients in intensive care you treat with these drugs, based on the evidence we saw, you would expect to save one life.” …
Tocilizumab and sarilumab have been added to the Government’s export restriction list, the Department of Health and Social Care (DHSC) said.
This will protect supply for UK patients by enforcing regulatory action on those who flout the restrictions, it added.
Commenting on the findings, Peter Horby, professor of Emerging Infectious Diseases, the University of Oxford’s Centre for Tropical Medicine and Global Health…
“Importantly, the findings of a benefit are in addition to corticosteroids, which were taken by 93 per cent of the participants.
“This means we now have two drugs, which combined have a greater effect.”

KEVZARA HELPS INHIBIT THE EFFECTS OF CHRONICALLY ELEVATED IL-6: KEVZARA targets and binds with high affinity to soluble and membrane-bound IL-6 receptors (sIL-6R and mIL-6R), thereby inhibiting IL-6 signaling | @sanofi & @Regeneron
Sarilumab-Kevzara1 mechanism

UK approves anti-inflammatory drugs to treat sickest covid-19 patients after strong results in clinical trial (01/08/2021) | @washingtonpost,@Carolynyjohnson,@bbguari
…Jonathan Parr…
David E. Leaf, a Harvard Medical School assistant professor and Brigham and Women’s Hospital physician, said the data were game-changing: “For ICU patients, I think it is a slam dunk that they should be given tocilizumab if it can be given early on.”…
“We’re currently live in 290 sites around the world, and so there was no way to quietly whisper to 290 sites: ‘Stop randomizing to control in the immune modulation arm, but don’t tell anyone,’ ” said Derek Angus, chair of critical care medicine at the University of Pittsburgh Medical Center and one of the investigators of the trial. …
The list price of the dose of Kevzara used in the trial is about $3,600. The maximum dose used in the trial of Actemra currently carries a list price of $4,600, but the dose varied by patients’ body weight and could be given either once or twice. Bob Purcell, a spokesman for Genentech, a member of the Roche Group, said that the drug was not approved for use in covid-19 and the pricing might differ if it were approved to treat the illness. …
About 36 percent of patients died in the hospital who received standard care, while 28 percent died on tocilizumab and 22 percent died when given sarilumab. Patients treated with the drugs spent about a week less in the ICU, on average. …

UK Approves Arthritis Drugs for Critically Ill COVID-19 Patients (01/11/2021) | @TheScientistLLC,@AsherGJones
… The study, which has not yet been peer-reviewed, evaluated around 800 patients in intensive care with severe COVID-19. Around half received the standard of care while 353 received tocilizumab and 48 received sarilumab. The researchers found that 35.8 percent of those given standard care died, compared with 28 percent who received tocilizumab and 22.2 percent who were given sarilumab. …
The immunosuppressive drugs tocilizumab and sarilumab, which are primarily used to treat arthritis, block signaling of the cytokine IL-6, a key regulator of immune dysregulation and inflammation in severe COVID-19 cases. …
…Krutika Kuppalli, an infectious disease physician at the Medical University of South Carolina… @nytimes
…Jonathan Parr, an infectious diseases physician at the University of North Carolina at Chapel Hill… @washingtonpost

Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis (04/03/2021) | National Center for Biotechnology Information, U.S. National Library of Medicine
Sarilumab-Kevzara4 NIH-RA-developmentSarilumab-Kevzara3 NIH-RApatients-strategySarilumab-Kevzara5 NIH-SideEffects

Kevzara (Sarilumab injection, for subcutaneous use): side effects (05/18/2018) | @RxList
Kevzara (sarilumab) injection is an interleukin-6 (IL-6) receptor antagonist indicated for treatment of adult patients with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response or intolerance to one or more disease-modifying antirheumatic drugs (DMARDs). Common side effects of Kevzara include:
・low white blood cell count (neutropenia),
・increased ALT,
・injection site redness,
・upper respiratory infections,
・nasal congestion,
・runny nose,
・sore throat,
・urinary tract infections, and
・low platelet counts (thrombocytopenia). …

Sarilumab (Kevzara®) Drug Information Sheet | @jhrheumatology
Sarilumab-Kevzara2 JH-SideEffects

Kevzara Side Effects (09/13/2020) | @Drugscom
Side effects requiring immediate medical attention
… Check with your doctor immediately if any of the following side effects occur while taking sarilumab:
More common
・Bloody, black, or tarry stools
・chills
・cough
・fever
・lower back or side pain
・painful or difficult urination
・pale skin
・sore throat
・ulcers, sores, or white spots in the mouth
・unusual bleeding or bruising
・unusual tiredness or weakness
Less common
・bladder pain
・bloody or cloudy urine
・body ache or pain
・difficulty breathing
・ear congestion
・frequent urge to urinate
・headache
・loss of voice
・nasal congestion
・painful cold sores or blisters on the lips
・runny nose
・sneezing
Rare
・difficulty swallowing
・dizziness
・fast heartbeat
・heartburn
・hives, itching, skin rash
・indigestion
・nausea
・puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
・severe stomach pain, cramping, or burning
・tightness in the chest
・vomiting of material that looks like coffee grounds, severe and continuing
Side effects not requiring immediate medical attention
More common
・bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
For Healthcare Professionals
Dermatologic; Hematologic; Hypersensitivity; Immunologic; Local; Metabolic; Genitourinary; Hepatic; Respiratory; General; Gastrointestinal

Kevzara (Sarilumab), a New IL-6 Receptor Antagonist, Approved for Active Rheumatoid Arthritis (03/2018) | American Health & Drug Benefits @TheLynxGroup
Mechanism of Action
Sarilumab is a human recombinant monoclonal antibody that binds to IL-6 receptors that inhibit IL-6?mediated signaling. The IL-6 cytokine plays a role in the body’s inflammatory process and response. The production of IL-6 by synovial and endothelial cells can lead to local production of IL-6 in the joints affected by RA and other inflammatory processes. Elevated levels of IL-6 have been correlated with disease activity and joint damage in patients with RA.
Dosing and Administration
The recommended dosage of sarilu-mab is 200 mg once every 2 weeks, administered as a subcutaneous injection; it is available as a 150-mg/1.14-mL or 200-mg/1.14-mL solution in a single-dose, prefilled syringe, and can be used as monotherapy or in combination with methotrexate or other conventional DMARDs. …
Adverse Reactions
The most common (incidence ≧3%) adverse reactions associated with saril-umab therapy are neutropenia (7%), increased alanine aminotransferase levels (5%), injection-site erythema (5%), upper respiratory infections (4%), and urinary tract infections (3%).
Drug Interactions
Cytokines and cytokine modulators can influence the activity of specific cytochrome (CY) P450 enzymes (including CYP3A4) and thus may alter the metabolism of drugs that are substrates of these enzymes. Use caution when sarilumab is co-administered with CYP3A4 substrate drugs for which decreased effectiveness is undesirable (eg, oral contraceptives, statins).
Use in Specific Populations
Nursing women may need to discontinue sarilumab or discontinue nursing.
No differences in safety or efficacy of sarilumab were seen between older (aged ≧65 years) and younger patients.
Warnings and Precautions
The prescribing information for saril-umab includes a boxed warning stating that sarilumab is associated with an increased risk for serious and potentially fatal infections, including bacterial, viral, invasive fungal, and other opportunistic infections. Patients should be monitored closely for infection while receiving sarilumab.
Sarilumab has been associated with reduced ANC, including neutropenia; a reduction in platelet counts; transaminase elevations; and lipid abnormalities.
The risk for gastrointestinal perforation may be increased when sarilumab is used concomitantly with NSAIDs or with corticosteroids.
Treatment with immunosuppressant drugs, including sarilumab, may increase the risk for malignancies.
Sarilumab should be discontinued immediately if anaphylaxis or a hypersensitivity reaction occurs.
Sarilumab should not be used with live vaccines.
* Kevzara (sarilumab) injection [prescribing information]. Tarrytown, NY: Regeneron Pharmaceuticals; Bridgewater, NJ: sanofi-aventis U.S.; May 2017.

Repurposed Drugs to Fight SARS-CoV-2, Tocilizumab and Sarilumab – Part 4 (04/15/2021) | @_Monocl
Tocilizumab and sarilumab reduce COVID-19 patient mortality by 8.5 percent, data shows (07/01/2021) | @PharmaReview
Kevzara (sarilumab) | @mnt
Sarilumab (Subcutaneous Route) | @MayoClinic
Efficacy and safety of sarilumab in patients with active rheumatoid arthritis (01/11/2018) | National Center for Biotechnology Information, U.S. National Library of Medicine
Sarilumab | @sciencedirect

World 世界情勢等 Vol.8

All the below links are in English.

取り急ぎ以下(内容事項一部抜粋ご参考まで)貼っておきます。

World Vol.59 cities,history StockMarket,volatility GlobalWealthReport BlackRock WasteManagement NZ Russia VaccineRollout,UK ND,SD,NE,KS,FL

World Vol.58 (U.S., Australia, etc.) BlackFriday grocers FedEx,DHL,UPS SickLeave Perth Taiwan China salmon TN,KY,NM,WY

World Vol.57 (Joe Biden, Janet Yellen, etc.) China HumanRights Europe Russia travel FinancialStability Lego,Colosseum MilkyWay Scotland county-by-county OR,AK,HI,NY,MA,MI

World Vol.56 (U.S., etc.) FederalReserveBanks Pfizer BioNTech Moderna top20counties MI,ME,MA,MT,MO,TX,WV,WY,CO,NE,ND,IA Canada UK(NI)

World Vol.55 (incl 2019) masks sanctuary Ecuador,chocolate NZ RCEP MD,NM,AZ,VA

World Vol.54 (Eastern Europe, U.S.) coronavirus GiantShoppingMall EuropeanCapitalOfCulture Montenegro esports OH,TN,UT,NM,ID,CO,IN,KY,TX,FL Quebec,Inuit

World Vol.53 (U.S., etc.)
この日付は11/3となっていますが、少々気を遣うあまり投稿しないまま忘れてしまっており、つい先程投稿しましたので、実質的日付は 12/9 です。
OnlineChess bookstores beaches Walmart bettors election FL,NC,SC,IN,OH

World Vol.52 (U.S.) food AbsenteeBallot MaskRequirements antitrust,monopoly AmyConeyBarrett AL,AR,TN,TX,NYC

Caucasus Vol.2 (2020 Nagorno-Karabakh War)

なお、先程発見した客観的事実として、弊社英語ウェブサイトの検索欄に「World Vol.」と入れると(そのURLは http://worldsolutions.work/?s=World+Vol. です)、
「 This page isn’t working  worldsolutions.work is currently unable to handle this request. HTTP ERROR 500 」
と出て来るようになってしまっています。
最近「World Vol.」シリーズでアメリカ国内の地方テレビ局のツイートを(あくまで一般感覚的に普通に)少々貼っておりましたが、それを検索されるのを好まない人達が居るということかと推察いたします。

Science and Technology 科学技術 Vol.18 / #Coronavirus #コロナウイルス Vol.21

All the below links are in English.

取り急ぎ以下(黒字部分は内容事項一部抜粋ご参考まで)貼っておきます。

Science and Technology Vol.49 COVID19 vaccines materials AI,robotics
Science and Technology Vol.48 (incl 2019) telehealth coronavirus pandemics MachineLearning triage ventilator nurses startup chemicals GPS HorizonEU electrification
Science and Technology Vol.47 (incl 2019) digitalhealth PhysicalDistancing immunotherapy food molecular metal
Science and Technology Vol.46 (personal protective equipment (PPE) suppliers/manufacturers) 
Science and Technology Vol.45 telemedicine COVID19vaccine ventilators vitaminD kidneyinjury,AKI periosteum
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